Cydia pomonella granulosis virus (CpGV) is a Baculovirus Granulovirus. It has a double-stranded DNA genome 123500 bp in length with 143 ORFs. The virus forms small bodies called granules containing a single viron. CpGV is a virus of invertebrates – specifically Cydia pomonella or the Codling moth. CpGV is highly pathogenic, it is known as a fast GV – that is, one that will kill its host in the same instar as infection; thus, it is frequently used as a biological pesticide.
C. pomonella has proved to be a problematic pest on several fruit trees, including apples and pears. The caterpillars burrow into the fruit, rendering it un-sellable. Traditional insecticides are of limited use, as some strains have acquired resistance to several insecticides.
CpGV has been shown to kill many of the larvae of C. pomonella in trials without having adverse effects on humans or other animals, thanks to the specific nature of the virus. Also, no development of resistance was observed. Know it is known that several resistant populations occurred.
A CpGV strain is available as commercial pesticides like CYD-X (Certis) and MADEX (Andermatt Biocontrol AG).